Behavioral Neuroscience, Eyeblink circuitry
USD Department of Biology
Behavioral Neuroscience
Summers
C. picta Turtle Eyeblink Behavior
Sensory Stimulation of Eyeblink
Eyeblink Motor Output
Neuromuscular Function
In vitro Conditioning
Glu
ACh
BDNF
text:Kandel pages 1243 & 849
Turtles and Ecology
Eyeblink Circuitry
end     Acronyms/Abbreviations
Eye Blink    back to

Mammalian Circuit:
1) Mouse

A putative eyeblink conditioning circuit based on experimental findings and gross anatomy of the cerebellum and the brain stem. The conditioned stimulus (CS) pathway consists of excitatory (+) mossy fiber (MF) projections from the pontine nuclei (PN) to the interpositus nucleus (Int) and to the cerebellar cortex. In the cortex, the mossy fibers form synapses with granule cells (GR) that in turn send excitatory parallel fibers to the Purkinje cells (PC). The Purkinje cells are the exclusive output neurons from the cortex and they send inhibitory () fibers to deep nuclei such as the interpositus. The unconditioned stimulus (US) pathway consists of excitatory climbing fiber (CF) projections from the inferior olive (IO) to the interpositus nucleus and to the Purkinje cells in the cerebellar cortex. Within the cerebellar cortex, Golgi (GO), stellate (ST) and basket (BA) cells exert inhibitory actions on their respective target neurons. The efferent conditioned response (CR) pathway projects from the interpositus nucleus to the red nucleus (RN) and via the descending rubral pathway to act ultimately on the eyeblink reflex path. Additional abbreviations: V Coch N, ventral cochlear nucleus; N V (sp), spinal fifth cranial nucleus; N VI, sixth cranial nucleus; N VII, seventh cranial nucleus; UR, unconditioned response.

Turtle Brains:
1) Turtle brains in relation to body

  Sea turtle brain in situ

2) Outline of Turtle Brain Regions
outline of turtle brain

3) Isolated Brainstem-Cerebellum preparation
Actual in vitro turtle brain

4) local neuroanatomy

5) Simple R1 circuit

6)R1 + R2 circuit