Laboratory of Molecular Neuropsychoecoendochemistry
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Summers' Lab Master's Alumni
Kevin Krupp, MS - 2018-2021
N3 Fellow
Yaeger JDW, KT Krupp, TR Summers, CH Summers 2022 Contextual generalization of social stress learning is modulated by
orexin receptors in basolateral amygdala. Neuropharmacology DOI: 10.1016/j.neuropharm.2022.109168
Yaeger JDW, KT Krupp, BM Jacobs, BO Onserio, BL Meyerink, JT Cain, PJ Ronan, KJ Renner, RJ DiLeone, CH Summers 2022
Orexin 1 receptor antagonism in basolateral amygdala shifts the balance from pro- to anti-stress signaling and behavior.
Biological Psychiatry 91: 841-852
Yaeger JDW, KT Krupp, JJ Gale, CH Summers 2020 Counter-balanced microcircuits for Orx1 and Orx2 regulation
of stress reactivity. Medicine in Drug Discovery 100059: 1-20
Currently:
Clarissa Staton, M.S. 2015-2018
Staton CD, JDW Yaeger, DD Khalid, F Haroun, BS Fernandez, JS Fernandez, BK Summers, TR Summers, M Sathyanesan, SS Newton, CH Summers
2018 Orexin 2 receptor stimulation enhances resilience, while orexin 2 inhibition promotes susceptibility, to social stress, anxiety and
depression. Neuropharmacology 143: 79-94.
Summers CH, JDW Yaeger, CD Staton, DH Arendt, TR Summers 2020 Orexin/hypocretin receptor modulation of anxiolytic and antidepressive
responses during social stress and decision-making: potential for therapy. Brain Research 1731: 146085: 1-15
Robertson JM, JK Achua, JP Smith, MA Prince, CD Staton, PJ Ronan, TR Summers, CH Summers 2017 Anxious behavior induces
elevated hippocampal Cb2 receptor gene expression. Neuroscience 352: 273-284
Currently: Research Specialist
Sanford Research
Sioux Falls, SD
Justin K. Achua, M.D., M.S. 2013-2016
Robertson JM, JK Achua, JP Smith, MA Prince, CD Staton, PJ Ronan, TR Summers, CH Summers 2017 Anxious behavior induces
elevated hippocampal Cb2 receptor gene expression. Neuroscience 352: 273-284
Smith JP, MA Prince, JK Achua, JM Robertson, RT Anderson, PJ Ronan, and CH Summers 2016 Intensity of anxiety is modified via complex
integrative stress circuitries. Psychoneuroendocrinology 63: 351-361
Robertson JM, MA Prince, JK Achua, RE Carpenter, DH Arendt, JP Smith, TL Summers, TR Summers, and CH Summers 2015 Nuance and behavioral
cogency: How the Visible Burrow System inspired the Stress-Alternatives Model and conceptualization of the continuum of anxiety.
Physiology and Behavior 146: 86-97
Arendt DH, J Hassell, Hao Li, JK Achua, DJ Guarnieri, RJ DiLeone, PJ Ronan, and CH Summers 2014 Anxiolytic function of the orexin 2 /
hypocretin A receptor in the basolateral amygdala. Psychoneuroendocrinology 40C: 17-26
Smith JP, JK Achua, TR Summers, PJ Ronan and CH Summers 2014 Neuropeptide S and BDNF gene
expression in the amygdala are influenced by social decision-making under stress.
Front Behav Neurosci 8:121: 1-13 doi: 10.3389/fnbeh.2014.00121
Currently: M.D.
Miller School of Medicine
University of Miami
Miami, FL
Travis J. Ling, MBA, M.S. 2005-2007
Ling TJ, CH Summers, KJ Renner and MJ Watt 2010 Opponent recognition and social status
differentiate rapid neuroendocrine responses to social challenge
Physiol Behav 99: 571-578
Ling TJ, GL Forster, MJ Watt, WJ Korzan, KJ Renner and CH Summers 2009 Social status
differentiates rapid neuroendocrine responses to restraint stress.
Physiol & Behav 96: 218-232
Summers, CH, MJ Watt, TL Ling, GL Forster, RE Carpenter, WJ Korzan,
JL Lukkes, Ø Øverli 2005 Glucocorticoid interaction with
aggression in non-mammalian vertebrates: Reciprocal action.
Eur J Parmacol 526: 21-35
Aaron Prestbo, M.A. 1998-2000, M.D.
Summers, CH, JL Kampshoff, PJ Ronan, CA Lowry, AA Prestbo, WJ Korzan
and KJ Renner 2003 Monoaminergic activity in subregions of raphé
nuclei elicited by prior stress and the neuropeptide corticotropin-
releasing factor Journal of Neuroendocrinology 15: 1122-1133
Wayne J. Korzan, M.A. 1998-1999, Ph.D. 2000-2004
Korzan WJ and CH Summers 2021 Evolution of stress responses refine mechanisms of social rank.
Neurobiology of Stress 100328: 1-19
Korzan WJ, TR Summers and CH Summers 2021 Neural and endocrine responses to social stress differ
during actual and virtual aggressive interactions or physiolgical sign stimuli. Biological Processes 182: 104294: 1-10
Korzan WJ, E Höglund, MJ Watt, GL Forster, Ø Øverli, JL Lukkes and CH Summers
2007 Memory of opponents is more potent than visual sign stimuli after
social hierarchy has been established. Behav Brain Res 183: 31-42
Korzan WJ and CH Summers 2007 Behavioral diversity and neurochemical plasticity:
Selection of stress coping strategies that define social status.
Brain Behav Evol 70: 257-266
Korzan WJ, GL Forster, MJ Watt, and CH Summers 2006 Dopaminergic
activity modulation via aggression, status and a visual social
signal. Behav Neurosci 120: 93-102
Korzan WJ, Ø Øverli and CH Summers 2006 Future social rank:
Forecasting status in the green anole (Anolis carolinensis)
Acta Ethologica 9: 48-57
Korzan WJ and CH Summers 2004 Serotonergic response to social stress
and artificial social sign stimuli during paired interactions
between male Anolis carolinensis. Neuroscience 123: 835-845
Korzan WJ, TR Summers and CH Summers 2002 Manipulation of visual sympathetic
sign stimulus modifies social status and plasma catecholamines.
General and Comparative Endocrinology 128: 153-161
Korzan WJ, TR Summers, PJ Ronan, KJ Renner and CH Summers 2001 The role
of monoaminergic perikarya during aggression and sympathetic social
signaling Brain Behavior and Evolution 57: 317-327
Korzan WJ, TR Summers, PJ Ronan and CH Summers 2000 Visible sympathetic
activity as a social signal in Anolis carolinensis: Changes in
aggression and plasma catecholamines Horm Behav 38: 193-199
Korzan WJ, TR Summers and CH Summers 2000 Monoaminergic activities
of limbic systems are elevated during aggression: Influence of
sympathetic social signaling Brain Research 870: 170-178
Carpenter RE, WJ Korzan, C Bockholt, MJ Watt, GL Forster, KJ Renner and CH Summers
2009 Corticotropin releasing factor influences aggression and monoamines:
Modulation of attacks and retreats. Neuroscience 158: 412-425
Ling TJ, GL Forster, MJ Watt, WJ Korzan, KJ Renner and CH Summers 2009 Social status
differentiates rapid neuroendocrine responses to restraint stress.
Physiol & Behav 96: 218-232
Shaw JC, WJ Korzan, RE Carpenter, AM Kuris, KD Lafferty, CH Summers, Ø Øverli 2009
Parasite manipulation of brain monoamines in California killifish (Fundulus parvipinnis)
by the trematode Euhaplorchis californiensis. Proc R Soc B 276: 1137-1146
Øverli Ø, C Sørensen, KGT Pulman, TG Pottinger, WJ Korzan, CH Summers
and G Nilsson 2007 Evolutionary background for stress coping styles:
Relationships between physiological, behavioral, and cognitive
traits in non-mammalian vertebrates Neurosci Biobehav Rev 31:
396-412
Watt MJ, GL Forster, WJ Korzan, KJ Renner and CH Summers 2007 Initial
perception of social threat rapidly alters neuroendocrine activity
Physiol Behav 90: 567-575
Forster GL, N Feng, MJ Watt, WJ Korzan, NJ Mouw, CH Summers and
KJ Renner 2006 Corticotropin-releasing factor in the dorsal
raphe elicits temporally distinct serotonergic responses in
the limbic system Neuroscience 141: 1047-1055
Forster GL, MJ Watt, WJ Korzan, KJ Renner and CH Summers 2005
Opponent recognition between male green anoles (Anolis
carolinensis). Anim Behav 69: 733-740
Höglund E, WJ Korzan, MJ Watt, GL Forster, TR Summers, H Falch
Johannessen, KJ Renner and CH Summers 2005 Effects of L-DOPA
on aggressive behavior and central monoaminergic activity in
the lizard Anolis carolinensis, using a new method for drug
delivery. Behav Brain Res 156: 53-64
Summers, CH, GL Forster, WJ Korzan, MJ Watt, ET Larson, Ø Øverli,
E Höglund, PJ Ronan, TR Summers, KJ Renner, N Greenberg 2005
Dynamics and mechanics of social rank reversal
J Comp Physiol A 191: 241-252
Summers CH, WJ Korzan, JL Lukkes, MJ Watt, GL Forster, Ø Øverli,
E Höglund, ET Larson, PJ Ronan, JM Matter, TR Summers, KJ Renner,
and N Greenberg 2005 Does serotonin influence aggression?
Comparing regional activity before and during social interaction
Physiol Biochem Zool 78: 679-694
Summers CH, MJ Watt, TL Ling, GL Forster, RE Carpenter, WJ Korzan,
JL Lukkes, Ø Øverli 2005 Glucocorticoid interaction with
aggression in non-mammalian vertebrates: Reciprocal action.
Eur J Parmacol 526: 21-35
Meyer, WN, J Keifer, WJ Korzan and CH Summers 2004 Social stress and
corticosterone regionally upregulate limbic N-methyl-D-Aspartate
Receptor (NR) subunit type NR2A and NR2B in the lizard Anolis
carolinensis. Neuroscience 128: 675-684
Øverli Ø, WJ Korzan, E Höglund, S Winberg, H Bollig, MJ Watt, GL Forster,
BA Barton, E Øverli, KJ Renner and CH Summers 2004 Stress coping style
predicts aggression and social dominance in rainbow trout.
Hormones & Behavior 45: 235-241
Øverli Ø, WJ Korzan, ET Larson, O Lepage, TG Pottinger, S Winberg, KJ Renner
and CH Summers 2004 Behavioral and neuroendocrine correlates of
displaced aggression in trout Hormones & Behavior 45: 324-329
Summers, CH, JL Kampshoff, PJ Ronan, CA Lowry, AA Prestbo, WJ Korzan
and KJ Renner 2003 Monoaminergic activity in subregions of raphé
nuclei elicited by prior stress and the neuropeptide corticotropin-
releasing factor Journal of Neuroendocrinology 15: 1122-1133
Summers, CH, TR Summers, MC Moore, WJ Korzan, SK Woodley, PJ Ronan,
E Höglund, MJ Watt and N Greenberg 2003 Temporal patterns
of limbic monoamine and plasma corticosterone response during
social stress Neuroscience 116: 553-563
Troy Gust, M.A., M.D. 1997-1998
Aaron J. Emerson, M.A. 1996-1997, J.D.
Waters, RP, AJ Emerson, MJ Watt, GL Forster, JG Swallow and CH Summers
2005 Stress induces rapid changes in central catecholaminergic
activity in Anolis carolinensis: Restraint and forced physical
activity. Brain Res Bull 67: 210-218
Emerson, AJ, DP Kappenman, PJ Ronan, KJ Renner and CH Summers 2000
Stress induces rapid changes in serotonergic activity: Restraint
and exertion Behav Brain Res 111: 83-92
Summers, CH, ET Larson, PJ Ronan, PM Hofmann, AJ Emerson, and KJ Renner 2000
Serotonergic responses to corticosterone and testosterone in the limbic
system General Comp Endocrinol 117: 151-159
Currently: Partner Attorney, Myers and Billion, LLP
300 North Dakota Avenue
Suite 510 P.O. Box 1085
Sioux Falls, SD 57101
Jen M. McKay, M.A. 1994-1996, M.D.
Summers, TR, JM Matter, JM McKay, PJ Ronan, ET Larson, KJ Renner and
CH Summers 2003 Rapid glucocorticoid stimulation and GABAergic
inhibition of hippocampal serotonergic response: In vivo dialysis
in the lizard Anolis carolinensis. Hormones & Behavior 43: 245-253
Patrick J. Ronan, M.A. 1994-1995, Ph.D. 1995-2000
Ronan PJ, WJ Korzan, PL Johnson, CA Lowry, KJ Renner, CH Summers 2023 Prior stress and vasopressin
promote corticotropin-releasing factor inhibition of serotonin release in the central nucleus
of the amygdala. Frontiers in Behavioral Neuroscience 17: 1148292: 1-14
Ronan PJ and CH Summers 2011 Molecular signaling and translational significance of
the corticotropin releasing factor system - Chap 6 In Progress in Molecular Biology
and Translational Science Vol 98 The Brain as a Drug Target, S Rahman ed,
Academic Press, Burlington pp. 235-292
Ronan PJ and CH Summers 2008 Biology, Animal Models in
Encyclopedia of Psychological Trauma, G Reyes, J Elhai, J Ford eds,
John Wiley & Sons, New York pp. 80-83
Ronan PJ, MP Gaikowski, SJ Hamilton, KJ Buhl and CH Summers 2007 Ammonia causes decreased brain monoamines in fathead minnows (Pimephales
promelas). Brain Res 1147: 184-191
Robertson JM, JK Achua, JP Smith, MA Prince, CD Staton, PJ Ronan, TR Summers, CH Summers 2017 Anxious behavior induces
elevated hippocampal Cb2 receptor gene expression. Neuroscience 352: 273-284
Smith JP, MA Prince, JK Achua, JM Robertson, RT Anderson, PJ Ronan, and CH Summers 2016 Intensity of anxiety is modified via complex
integrative stress circuitries. Psychoneuroendocrinology 63: 351-361
Arendt DH, J Hassell, Hao Li, JK Achua, DJ Guarnieri, RJ DiLeone, PJ Ronan, and CH Summers 2014 Anxiolytic function of the orexin 2 /
hypocretin A receptor in the basolateral amygdala. Psychoneuroendocrinology 40C: 17-26
Smith JP, JK Achua, TR Summers, PJ Ronan and CH Summers 2014 Neuropeptide S and BDNF gene
expression in the amygdala are influenced by social decision-making under stress.
Front Behav Neurosci 8:121: 1-13 doi: 10.3389/fnbeh.2014.00121
Arendt DH, PJ Ronan, KD Oliver, LB Callahan,TR Summers and CH Summers 2013 Depressive
behavior and activation of the orexin/hypocretin system Behav Neurosci 127:86-94
Summers, CH, GL Forster, WJ Korzan, MJ Watt, ET Larson, Ø Øverli,
E Höglund, PJ Ronan, TR Summers, KJ Renner, N Greenberg 2005
Dynamics and mechanics of social rank reversal
J Comp Physiol A 191: 241-252
Summers, CH, WJ Korzan, JL Lukkes, MJ Watt, GL Forster, Ø Øverli,
E Höglund, ET Larson, PJ Ronan, JM Matter, TR Summers, KJ Renner,
and N Greenberg 2005 Does serotonin influence aggression?
Comparing regional activity before and during social interaction
Physiol Biochem Zool 78: 679-694
Ten Eyck, GR, PJ Ronan, KJ Renner and CH Summers 2005 Serotonin
metabolism in directly developing frog embryos during paternal
care. Neurosci Lett 388: 100-105
Summers, CH, JL Kampshoff, PJ Ronan, CA Lowry, AA Prestbo, WJ Korzan
and KJ Renner 2003 Monoaminergic activity in subregions of raphé
nuclei elicited by prior stress and the neuropeptide corticotropin-
releasing factor Journal of Neuroendocrinology 15: 1122-1133
Summers, CH, TR Summers, MC Moore, WJ Korzan, SK Woodley, PJ Ronan,
E Höglund, MJ Watt and N Greenberg 2003 Temporal patterns
of limbic monoamine and plasma corticosterone response during
social stress Neuroscience 116: 553-563
Summers, TR, JM Matter, JM McKay, PJ Ronan, ET Larson, KJ Renner and
CH Summers 2003 Rapid glucocorticoid stimulation and GABAergic
inhibition of hippocampal serotonergic response: In vivo dialysis
in the lizard Anolis carolinensis. Hormones & Behavior 43: 245-253
Korzan WJ, TR Summers, PJ Ronan, KJ Renner and CH Summers 2001 The role
of monoaminergic perikarya during aggression and sympathetic social
signaling Brain Behavior and Evolution 57: 317-327
Emerson, AJ, DP Kappenman, PJ Ronan, KJ Renner and CH Summers 2000
Stress induces rapid changes in serotonergic activity: Restraint
and exertion Behav Brain Res 111: 83-92
Korzan, WJ, TR Summers, PJ Ronan and CH Summers 2000 Visible sympathetic
activity as a social signal in Anolis carolinensis: Changes in
aggression and plasma catecholamines Horm Behav 38: 193-199
Summers, CH, ET Larson, PJ Ronan, PM Hofmann, AJ Emerson, and KJ Renner 2000
Serotonergic responses to corticosterone and testosterone in the limbic
system General Comp Endocrinol 117: 151-159
Deckel, AW, R Lillianey, PJ Ronan and CH Summers 1998 Lateralized effects
of ethanol on aggression and serotonergic systems. Brain Research
807: 38-46.
Matter, JM, PJ Ronan and CH Summers 1998 Central monoamines in free
ranging lizards: Differences associated with social roles and
territoriality Brain Behavior Evolution 51: 23-32.
currently:
Veterans Affairs Research Service
Sioux Falls VA Health Care System
Sioux Falls, SD 57105, USA
and
Associate Professor
Department of Psychiatry
Sanford Schol of Medicine
University of South Dakota
1400 W. 22nd Street
Sioux Falls, SD 57105
Tom Andrews, MA 1992-1994
Andrews, TJ and CH Summers 1996 Aggression, and the acquisition and
social function of dominance in female green anoles, Anolis
carolinensis. Behaviour 133: 1265-1279.
Mark Gaikowski, MA 1992-1994
Gaikowski, MP, SJ Hamilton, KJ Buhl, SF McDonald, and CH Summers 1996
Acute toxicity of three fire retardant and two fire suppressant foam
formulations to the early life stages of rainbow trout
(Onchorhynchus mykiss) Env Toxicol Chem 15: 1365-1374.
Gaikowski, MP, SJ Hamilton, KJ Buhl, SF McDonald, and CH Summers 1996
Acute toxicity of fire fighting chemical formulations to four life
stages of fathead minnow. Ecotoxicol. Env. Safety 34: 252-263.
Teresa L. Grant, MNS 1991-1992
Summers, CH, DA Suedkamp, and TL Grant 1995 Regulation of ovarian
recrudescence: Effects of social interaction on female lizards,
Anolis carolinensis. J Exp Zool 271: 235-241
Neuroscience Group at USD
Biology Department
Summers' Biology Webpage
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Contact Us
Email Dr. Summers: 
Cliff@USD.Edu