Summers Lab
Laboratory of Molecular Neuropsychoecoendochemistry
Publications including student co-authorship
Graduate Students* in bold italics, undergraduate students in bold alone, postdocs* in italics
*Includes publications after graduations or completetion of postdoctoral training
Krupp KT, JDW Yaeger, LJ Ledesma, MHH Withanage, JJ Gale, CB Howe, TJ Allen, M Sathyanesan, SS Newton,
CH Summers 2024 Single administration of a psychedelic [(R)-DOI] influences coping strategies
to an escapable social stress. Neuropharmacology 252: 109949: 1-15.
Ronan PJ, WJ Korzan, PL Johnson, CA Lowry, KJ Renner, CH Summers 2023 Prior stress and vasopressin
promote corticotropin-releasing factor inhibition of serotonin release in the central nucleus
of the amygdala. Frontiers in Behavioral Neuroscience 17: 1148292: 1-14
Carpenter RE, B Sabirzhanov, TR Summers, TG Clark, J Keifer and CH Summers 2022 Anxiolytic reversal of classically conditioned /
chronic stress-induced gene expression and learning in the stress alternatives model. Behavioural Brain Research
114258 https://doi.org/10.1016/j.bbr.2022.114258
Yaeger JDW, KT Krupp, TR Summers, CH Summers 2022 Contextual generalization of social stress learning is modulated by
orexin receptors in basolateral amygdala. Neuropharmacology DOI: 10.1016/j.neuropharm.2022.109168
Yaeger JDW, KT Krupp, BM Jacobs, BO Onserio, BL Meyerink, JT Cain, PJ Ronan, KJ Renner, RJ DiLeone, CH Summers 2022
Orexin 1 receptor antagonism in basolateral amygdala shifts the balance from pro- to anti-stress signaling and behavior.
Biological Psychiatry 91: 841-852
Korzan WJ and CH Summers 2021 Evolution of stress responses refine mechanisms of social rank.
Neurobiology of Stress 100328: 1-19
Pang T, JDW Yaeger, CH Summers, and R Mitra 2021 Cardinal role of the environment in stress induced changes
across life stages and generations. Neuroscience and Biobehavioral Reviews 124: 137-150
Yaeger JDW, KT Krupp, JJ Gale, CH Summers 2020 Counter-balanced microcircuits for Orx1 and Orx2 regulation
of stress reactivity. Medicine in Drug Discovery doi.org/10.1016/j.medidd.2020.100059
Summers CH, JDW Yaeger, CD Staton, DH Arendt, TR Summers 2020 Orexin/hypocretin receptor modulation of anxiolytic and antidepressive
responses during social stress and decision-making: potential for therapy. Brain Research 1731: 146085: 1-15
Robertson JM, AR Cahlander-Mooers, CH Summers and MD Dixon 2019 Population condition of Populus xsmithii,
a pleistocene relict aspen of the Niobrara River valley, Nebraska, USA. Natural Areas Journal 39: 286-296
Staton CD, JDW Yaeger, DD Khalid, F Haroun, BS Fernandez, JS Fernandez, BK Summers, TR Summers, M Sathyanesan, SS Newton, CH Summers
2018 Orexin 2 receptor stimulation enhances resilience, while orexin 2 inhibition promotes susceptibility, to social stress, anxiety and
depression. Neuropharmacology 143: 79-94.
Robertson JM, JK Achua, JP Smith, MA Prince, CD Staton, PJ Ronan, TR Summers, CH Summers 2017 Anxious behavior induces
elevated hippocampal Cb2 receptor gene expression. Neuroscience 352: 273-284
Summers TR, TL Summers, RE Carpenter, JP Smith, SL Young, B Meyerink, TZ Orr, DH Arendt, and CH Summers 2017 Learning and CRF-induced
indecision during escape and submission in rainbow trout during socially aggressive interactions in the Stress-Alternatives Model
Frontiers in Neuroscience 11: 515: 1-13
Smith JP, MA Prince, JK Achua, JM Robertson, RT Anderson, PJ Ronan, and CH Summers 2016 Intensity of anxiety is modified via complex
integrative stress circuitries. Psychoneuroendocrinology 63: 351-361
Waters RP, M Rivalan, D Bangasser, J Deussing, M Ising, SK Wood, F Holsboer, CH Summers 2015 Evidence for the role of
corticotropin-releasing factor in major depression disorder Neuroscience & Biobehavioral Reviews 63: 351-361
Robertson JM, MA Prince, JK Achua, RE Carpenter, DH Arendt, JP Smith, TL Summers, TR Summers, and CH Summers 2015 Nuance and behavioral
cogency: How the Visible Burrow System inspired the Stress-Alternatives Model and conceptualization of the continuum of anxiety.
Physiology and Behavior 146: 86-97
Arendt DH, J Hassell, Hao Li, JK Achua, DJ Guarnieri, RJ DiLeone, PJ Ronan, and CH Summers 2014
Anxiolytic function of the orexin 2 /hypocretin A receptor in the basolateral amygdala.
Psychoneuroendocrinology 40C: 17-26
Smith JP, JK Achua, TR Summers, PJ Ronan and CH Summers 2014 Neuropeptide S and BDNF gene
expression in the amygdala are influenced by social decision-making under stress.
Front Behav Neurosci 8:121: 1-13 doi: 10.3389/fnbeh.2014.00121
Arendt DH, PJ Ronan, KD Oliver, LB Callahan,TR Summers and CH Summers 2013 Depressive
behavior and activation of the orexin/hypocretin system Behav Neurosci 127:86-94
Ricci L+, CH Summers+, Larson ET+, D O’Malley and RH Melloni 2013 Development of aggressive phenotypes:
Interactions of age, experience, and social status. Animal Behaviour 86: 245-252 +equal contribution
Arendt DH, JP Smith, CC Bastida, M Prasad, KD Oliver, KM Eyster, TR Summers, Y Delville
and CH Summers 2012 Contrasting hippocampal and amygdalar expression of genes related
to neural plasticity during escape from social aggression. Phys Behav 107:670-679
Sørensen C, GE Nilsson, CH Summers and Ø Øverli 2011 Social stress reduces forebrain
cell proliferation in rainbow trout (Oncorhynchus mykiss).
Behav Brain Res 227: 311-318
Ronan PJ and CH Summers 2011 Molecular signaling and translational significance of
the corticotropin releasing factor system - Chap 6 In Progress in Molecular Biology
and Translational Science Vol 98 The Brain as a Drug Target, S Rahman ed,
Academic Press, Burlington pp. 235-292
Clotfelter ED, MM McNitt, RE Carpenter and CH Summers 2010 Modulation of monoamine
neurotransmitters in fighting fish Betta splendens exposed to waterborne
phytoestrogens Fish Physiol Biochem 36: 933-943
Ling TJ, CH Summers, KJ Renner and MJ Watt 2010 Opponent recognition and social status
differentiate rapid neuroendocrine responses to social challenge
Physiol Behav 99: 571-578
Waters RP, KJ Renner, CH Summers, MJ Watt, GL Forster, LG Koch, SL Britten, JG Swallow 2010
Selection for intrinsic endurance modifies endocrine stress responsiveness Brain Res 1357: 53-61
Carpenter RE and CH Summers 2009 Learning strategies during fear conditioning
Neurobiology of Learning and Memory 91: 415-423
Carpenter RE, WJ Korzan, C Bockholt, MJ Watt, GL Forster, KJ Renner and CH Summers
2009 Corticotropin releasing factor influences aggression and monoamines:
Modulation of attacks and retreats. Neuroscience 158: 412-425
Ling TJ, GL Forster, MJ Watt, WJ Korzan, KJ Renner and CH Summers 2009 Social status
differentiates rapid neuroendocrine responses to restraint stress.
Physiol & Behav 96: 218-232
Lorenzi V, RE Carpenter, CH Summers, RL Earley and MS Grober 2009 Serotonin, social status and
sex change in the bluebanded goby Lythrypnus dalli. Physiol Behav 97: 476-483
Lukkes JL, CH Summers, JL Scholl, KJ Renner and GL Forster 2009 Early life social
isolation alters corticotropin-releasing factor responses in adult rats
Neuroscience 158: 845-855
Shaw JC, WJ Korzan, RE Carpenter, AM Kuris, KD Lafferty, CH Summers, Ø Øverli 2009
Parasite manipulation of brain monoamines in California killifish (Fundulus parvipinnis)
by the trematode Euhaplorchis californiensis. Proc R Soc B 276: 1137-1146
Forster GL, RB Pringle, NJ Mouw, SM Vuong, MJ Watt, AR Burke, CA Lowry, CH Summers
and KJ Renner 2008 Corticotrophin-releasing factor in the dorsal raphé increases
medial prefrontal cortical serotonin via type 2 receptors and median raphé
activity. Eur J Neuroscience 28: 299-310
Lukkes JL, GL Forster, KJ Renner and CH Summers 2008 Corticotropin-releasing
factor 1 and 2 receptors in the dorsal raphé differentially affect serotonin
release in the nucleus accumbens. Eur J Pharmacol 578: 185-193
Ronan PJ and CH Summers 2008 Biology, Animal Models in
Encyclopedia of Psychological Trauma, G Reyes, J Elhai, J Ford eds,
John Wiley & Sons, New York pp. 80-83
Waters RP, KJ Renner, RB Pringle, CH Summers, SL Britton, LG Koch, JG Swallow 2008
Selection for aerobic capacity affects corticosterone, monoamines and
wheel-running activity Physiol & Behav 93: 1044-1054
Carpenter RE, MJ Watt, GL Forster, Ø Øverli, C Bockholt, KJ Renner and CH Summers
2007 Corticotropin releasing factor induces anxiogenic locomotion in trout and
alters serotonergic and dopaminergic activity. Horm & Behav 52: 600-611
Clotfelter ED, EP O'Hare, MM McNitt, RE Carpenter and CH Summers 2007
Pharmacological manipulation of the serotonergic system affects aggressive
behavior and brain monoamine levels in the fighting fish Betta splendens.
Pharmacol, Biochem Behav 87: 222-31
Korzan WJ, E Höglund, MJ Watt, GL Forster, Ø Øverli, JL Lukkes and CH Summers
2007 Memory of opponents is more potent than visual sign stimuli after
social hierarchy has been established. Behav Brain Res 183: 31-42
Korzan WJ and CH Summers 2007 Behavioral diversity and neurochemical plasticity:
Selection of stress coping strategies that define social status.
Brain Behav Evol 70: 257-266
Øverli Ø, C Sørensen, KGT Pulman, TG Pottinger, WJ Korzan, CH Summers
and G Nilsson 2007 Evolutionary background for stress coping styles:
Relationships between physiological, behavioral, and cognitive
traits in non-mammalian vertebrates Neurosci Biobehav Rev 31:
396-412
Ronan PJ, MP Gaikowski, SJ Hamilton, KJ Buhl and CH Summers 2007
Ammonia causes decreased brain monoamines in fathead minnows
(Pimephales promelas). Brain Res 1147: 184-191
Sørensen C, Ø Øverli, CH Summers, G Nilsson 2007 Social regulation
of neurogenesis in teleosts. Brain Behav Evol 70: 239-246
Watt MJ, GL Forster, WJ Korzan, KJ Renner and CH Summers 2007 Initial
perception of social threat rapidly alters neuroendocrine activity
Physiol Behav 90: 567-575
Forster GL, N Feng, MJ Watt, WJ Korzan, NJ Mouw, CH Summers and
KJ Renner 2006 Corticotropin-releasing factor in the dorsal
raphe elicits temporally distinct serotonergic responses in
the limbic system Neuroscience 141: 1047-1055
Korzan WJ, GL Forster, MJ Watt, and CH Summers 2006 Dopaminergic
activity modulation via aggression, status and a visual social
signal. Behav Neurosci 120: 93-102
Korzan WJ, Ø Øverli and CH Summers 2006 Future social rank:
Forecasting status in the green anole (Anolis carolinensis)
Acta Ethologica 9: 48-57
Forster, GL, MJ Watt, WJ Korzan, KJ Renner and CH Summers 2005
Opponent recognition between male green anoles (Anolis
carolinensis). Anim Behav 69: 733-740
Höglund E, WJ Korzan, MJ Watt, GL Forster, TR Summers, H Falch
Johannessen, KJ Renner and CH Summers 2005 Effects of L-DOPA
on aggressive behavior and central monoaminergic activity in
the lizard Anolis carolinensis, using a new method for drug
delivery. Behav Brain Res 156: 53-64
Summers, CH, GL Forster, WJ Korzan, MJ Watt, ET Larson, Ø Øverli,
E Höglund, PJ Ronan, TR Summers, KJ Renner, N Greenberg 2005
Dynamics and mechanics of social rank reversal
J Comp Physiol A 191: 241-252
Summers, CH, WJ Korzan, JL Lukkes, MJ Watt, GL Forster, Ø Øverli,
E Höglund, ET Larson, PJ Ronan, JM Matter, TR Summers, KJ Renner,
and N Greenberg 2005 Does serotonin influence aggression?
Comparing regional activity before and during social interaction
Physiol Biochem Zool 78: 679-694
Summers, CH, MJ Watt, TL Ling, GL Forster, RE Carpenter, WJ Korzan,
JL Lukkes, Ø Øverli 2005 Glucocorticoid interaction with
aggression in non-mammalian vertebrates: Reciprocal action.
Eur J Parmacol 526: 21-35
Ten Eyck, GR, WJ Jermakowicz, AF Chinn and CH Summers 2005 Ontogeny of
central serotonergic neurons in the directly developing frog,
Eleutherodactylus coqui. Anat & Embryol 210: 221-233
Ten Eyck, GR, PJ Ronan, KJ Renner and CH Summers 2005 Serotonin
metabolism in directly developing frog embryos during paternal
care. Neurosci Lett 388: 100-105
Waters, RP, AJ Emerson, MJ Watt, GL Forster, JG Swallow and CH Summers
2005 Stress induces rapid changes in central catecholaminergic
activity in Anolis carolinensis: Restraint and forced physical
activity. Brain Res Bull 67: 210-218
Korzan, WJ and CH Summers 2004 Serotonergic response to social stress
and artificial social sign stimuli during paired interactions
between male Anolis carolinensis. Neuroscience 123: 835-845
Larson, ET, S Winberg, I Mayer, O LePage, CH Summers and Ø Øverli 2004
Social stress affects circulating melatonin levels in rainbow trout.
Geneneral and Compomparative Endocrinology 136: 322-327
Meyer, WN, J Keifer, WJ Korzan and CH Summers 2004 Social stress and
corticosterone regionally upregulate limbic N-methyl-D-Aspartate
Receptor (NR) subunit type NR2A and NR2B in the lizard Anolis
carolinensis. Neuroscience 128: 675-684
Øverli, Ø, WJ Korzan, E Höglund, S Winberg, H Bollig, MJ Watt, GL Forster,
BA Barton, E Øverli, KJ Renner and CH Summers 2004 Stress coping style
predicts aggression and social dominance in rainbow trout.
Hormones & Behavior 45: 235-241
Øverli, Ø, WJ Korzan, ET Larson, O Lepage, TG Pottinger, S Winberg, KJ Renner
and CH Summers 2004 Behavioral and neuroendocrine correlates of
displaced aggression in trout Hormones & Behavior 45: 324-329
Larson, ET, DO Norris, EG Grau and CH Summers 2003 Monoamines stimulate
sex reversal in the saddleback wrasse General and Comparative
Endocrinology 130: 289-298
Larson, ET, DO Norris and CH Summers 2003 Monoaminergic
changes associated with socially induced sex reversal
in the saddleback wrasse Neuroscience 119: 251-263
Summers, CH, JL Kampshoff, PJ Ronan, CA Lowry, AA Prestbo, WJ Korzan
and KJ Renner 2003 Monoaminergic activity in subregions of raphé
nuclei elicited by prior stress and the neuropeptide corticotropin-
releasing factor Journal of Neuroendocrinology 15: 1122-1133
Summers, CH, TR Summers, MC Moore, WJ Korzan, SK Woodley, PJ Ronan,
E Höglund, MJ Watt and N Greenberg 2003 Temporal patterns
of limbic monoamine and plasma corticosterone response during
social stress Neuroscience 116: 553-563
Summers TR, JM Matter, JM McKay, PJ Ronan, ET Larson, KJ Renner and
CH Summers 2003 Rapid glucocorticoid stimulation and GABAergic
inhibition of hippocampal serotonergic response: In vivo dialysis
in the lizard Anolis carolinensis. Hormones & Behavior 43: 245-253
Hoffman CS, TM Westin, HM Miner, PL Johnson, CH Summers and KJ Renner 2002
GABAergic drugs alter hypothalamic serotonin release and lordosis in
estrogen-primed rats. Brain Research 946: 96-103
Korzan WJ, TR Summers and CH Summers 2002 Manipulation of visual sympathetic
sign stimulus modifies social status and plasma catecholamines.
General and Comparative Endocrinology 128: 153-161
Korzan WJ, TR Summers, PJ Ronan, KJ Renner and CH Summers 2001 The role
of monoaminergic perikarya during aggression and sympathetic social
signaling Brain Behavior and Evolution 57: 317-327
Larson, ET and CH Summers 2001 Serotonin reverses dominant social
status Behavioral Brain Research 121: 95-102
Emerson, AJ, DP Kappenman, PJ Ronan, KJ Renner and CH Summers 2000
Stress induces rapid changes in serotonergic activity: Restraint
and exertion Behav Brain Res 111: 83-92
Korzan WJ, TR Summers, PJ Ronan and CH Summers 2000 Visible sympathetic
activity as a social signal in Anolis carolinensis: Changes in
aggression and plasma catecholamines Horm Behav 38: 193-199
Korzan WJ, TR Summers and CH Summers 2000 Monoaminergic activities
of limbic systems are elevated during aggression: Influence of
sympathetic social signaling Brain Research 870: 170-178
Summers, CH, ET Larson, PJ Ronan, PM Hofmann, AJ Emerson, and KJ Renner 2000
Serotonergic responses to corticosterone and testosterone in the limbic
system General Comp Endocrinol 117: 151-159
Larson, ET, DO Norris, EG Grau and CH Summers 1999 Central monoaminergic
changes accompany sex reversal in the saddleback wrasse In
Norberg, B, OS Kjesbu, GL Taranger et. al. (eds.) Proc 6th Int Symp
Repro Physiol Fish, 53-55
Deckel, AW, R Lillianey, PJ Ronan and CH Summers 1998 Lateralized effects
of ethanol on aggression and serotonergic systems. Brain Research
807: 38-46.
Matter, JM, PJ Ronan and CH Summers 1998 Central monoamines in free
ranging lizards: Differences associated with social roles and
territoriality Brain Behavior Evolution 51: 23-32.
Summers, CH, ET Larson, TR Summers, KJ Renner and N Greenberg 1998
Regional and temporal separation of serotonergic activity mediating
social stress Neuroscience 87: 489-496.
Summers, TR, AL Hunter and CH Summers 1997 Female social reproductive roles
affect central monoamines Brain Research 767: 272-278.
Andrews, TJ and CH Summers 1996 Aggression, and the acquisition and
social function of dominance in female green anoles, Anolis
carolinensis. Behaviour 133: 1265-1279.
Gaikowski, MP, SJ Hamilton, KJ Buhl, SF McDonald, and CH Summers 1996
Acute toxicity of three fire retardant and two fire suppressant foam
formulations to the early life stages of rainbow trout
(Onchorhynchus mykiss) Env Toxicol Chem 15: 1365-1374.
Gaikowski, MP, SJ Hamilton, KJ Buhl, SF McDonald, and CH Summers 1996
Acute toxicity of fire fighting chemical formulations to four life
stages of fathead minnow. Ecotoxicol. Env. Safety 34: 252-263.
Summers, CH, DA Suedkamp, and TL Grant 1995 Regulation of ovarian
recrudescence: Effects of social interaction on female lizards,
Anolis carolinensis. J. Exp. Zool. 271: 235-241.
Published Abstracts
Publications from studies on Fish
Publications from studies on Amphibians
Publications from studies on Lizards
Publications from studies on Rodents
